Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | BIOCARTA_KERATINOCYTE DIFFERENTIATION |
| Enrichment Score (ES) | -0.6949569 |
| Normalized Enrichment Score (NES) | -1.5687705 |
| Nominal p-value | 0.0024937657 |
| FDR q-value | 0.31261152 |
| FWER p-Value | 0.856 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPK13 | 6760215 | 1290 | 0.661 | -0.0365 | No | ||
| 2 | HRAS | 1980551 | 1508 | 0.558 | -0.0203 | No | ||
| 3 | MAPK3 | 580161 4780035 | 1667 | 0.499 | -0.0040 | No | ||
| 4 | GRB2 | 6650398 | 2319 | 0.313 | -0.0234 | No | ||
| 5 | ETS1 | 5270278 6450717 6620465 | 3175 | 0.142 | -0.0624 | No | ||
| 6 | PPP2R5D | 4010156 380408 5550112 5670162 | 3414 | 0.116 | -0.0694 | No | ||
| 7 | MAP2K2 | 4590601 | 3424 | 0.115 | -0.0641 | No | ||
| 8 | FAS | 4480112 6110040 | 3467 | 0.111 | -0.0609 | No | ||
| 9 | PRKCA | 6400551 | 3576 | 0.103 | -0.0616 | No | ||
| 10 | CEBPA | 5690519 | 5330 | 0.035 | -0.1543 | No | ||
| 11 | EGFR | 4920138 6480521 | 5695 | 0.028 | -0.1725 | No | ||
| 12 | MAP2K7 | 2260086 | 6457 | 0.019 | -0.2125 | No | ||
| 13 | PLAT | 6860128 | 6469 | 0.019 | -0.2122 | No | ||
| 14 | RIPK1 | 3190025 | 6667 | 0.017 | -0.2219 | No | ||
| 15 | PRKCH | 5720079 | 6807 | 0.016 | -0.2286 | No | ||
| 16 | FOS | 1850315 | 7390 | 0.012 | -0.2594 | No | ||
| 17 | SOS1 | 7050338 | 7726 | 0.010 | -0.2769 | No | ||
| 18 | PRKCE | 5700053 | 10501 | 0.001 | -0.4262 | No | ||
| 19 | PRKCQ | 2260170 3870193 | 11610 | -0.002 | -0.4858 | No | ||
| 20 | MAP2K3 | 5570193 | 11950 | -0.003 | -0.5039 | No | ||
| 21 | TNF | 6650603 | 12391 | -0.005 | -0.5273 | No | ||
| 22 | MAP3K5 | 6020041 6380162 | 12783 | -0.007 | -0.5481 | No | ||
| 23 | JUN | 840170 | 13846 | -0.016 | -0.6045 | No | ||
| 24 | EGF | 5220154 | 14388 | -0.028 | -0.6322 | No | ||
| 25 | PRKCD | 770592 | 14741 | -0.043 | -0.6490 | No | ||
| 26 | BIRC3 | 6550411 | 14812 | -0.047 | -0.6504 | No | ||
| 27 | FASLG | 2810044 | 15163 | -0.069 | -0.6659 | No | ||
| 28 | SHC1 | 2900731 3170504 6520537 | 15309 | -0.081 | -0.6696 | No | ||
| 29 | IKBKG | 3450092 3840377 6590592 | 15397 | -0.091 | -0.6698 | No | ||
| 30 | BIRC2 | 2940435 4730020 | 15427 | -0.093 | -0.6667 | No | ||
| 31 | MAP2K1 | 840739 | 15475 | -0.098 | -0.6644 | No | ||
| 32 | MAPK1 | 3190193 6200253 | 15968 | -0.160 | -0.6829 | Yes | ||
| 33 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 15995 | -0.163 | -0.6762 | Yes | ||
| 34 | DAXX | 4010647 | 16292 | -0.214 | -0.6814 | Yes | ||
| 35 | MAP2K4 | 5130133 | 16544 | -0.277 | -0.6812 | Yes | ||
| 36 | MAPK8 | 2640195 | 16564 | -0.281 | -0.6682 | Yes | ||
| 37 | IKBKB | 6840072 | 16617 | -0.298 | -0.6561 | Yes | ||
| 38 | MAP4K4 | 2360059 | 16726 | -0.329 | -0.6455 | Yes | ||
| 39 | SP1 | 6590017 | 16789 | -0.347 | -0.6316 | Yes | ||
| 40 | RELA | 3830075 | 16834 | -0.358 | -0.6161 | Yes | ||
| 41 | RAF1 | 1770600 | 16929 | -0.388 | -0.6018 | Yes | ||
| 42 | CHUK | 7050736 | 17374 | -0.567 | -0.5974 | Yes | ||
| 43 | MAPK14 | 5290731 | 17410 | -0.583 | -0.5702 | Yes | ||
| 44 | MAP2K6 | 1230056 2940204 | 17445 | -0.603 | -0.5420 | Yes | ||
| 45 | NFKBIA | 1570152 | 17455 | -0.610 | -0.5120 | Yes | ||
| 46 | HOXA7 | 5910152 | 17605 | -0.687 | -0.4858 | Yes | ||
| 47 | TRAF2 | 5900148 | 17846 | -0.847 | -0.4565 | Yes | ||
| 48 | TRAF1 | 3440735 | 17963 | -0.948 | -0.4154 | Yes | ||
| 49 | MAP3K1 | 5360347 | 18485 | -2.116 | -0.3380 | Yes | ||
| 50 | ETS2 | 360451 | 18573 | -2.835 | -0.2013 | Yes | ||
| 51 | TNFRSF1A | 1090390 6520735 | 18609 | -4.080 | 0.0004 | Yes |
